diff --git a/crates/typst-layout/src/math/run.rs b/crates/typst-layout/src/math/run.rs
index b5e855188..c9772c66f 100644
--- a/crates/typst-layout/src/math/run.rs
+++ b/crates/typst-layout/src/math/run.rs
@@ -319,6 +319,24 @@ impl MathRun {
 
         let mut iter = self.0.into_iter().peekable();
         while let Some(fragment) = iter.next() {
+            if let MathFragment::Fractional(fr) = fragment {
+                if !empty {
+                    let mut frame_prev =
+                        std::mem::replace(&mut frame, Frame::soft(Size::zero()));
+
+                    finalize_frame(&mut frame_prev, x, ascent, descent);
+                    items.push(InlineItem::Frame(frame_prev));
+                    empty = true;
+
+                    x = Abs::zero();
+                    ascent = Abs::zero();
+                    descent = Abs::zero();
+                }
+
+                items.push(InlineItem::Fractional(fr));
+                continue;
+            }
+
             let class = fragment.class();
             let y = fragment.ascent();
 
diff --git a/tests/ref/math-spacing-fractional-inline.png b/tests/ref/math-spacing-fractional-inline.png
new file mode 100644
index 000000000..7ca0a5c59
Binary files /dev/null and b/tests/ref/math-spacing-fractional-inline.png differ
diff --git a/tests/ref/math-spacing-mixed-inline.png b/tests/ref/math-spacing-mixed-inline.png
new file mode 100644
index 000000000..ed3be05e6
Binary files /dev/null and b/tests/ref/math-spacing-mixed-inline.png differ
diff --git a/tests/suite/math/spacing.typ b/tests/suite/math/spacing.typ
index 55dcc2333..464805c82 100644
--- a/tests/suite/math/spacing.typ
+++ b/tests/suite/math/spacing.typ
@@ -87,6 +87,22 @@ Hello $#box(width: 40%)$ world \
 $mtext("Hello") #h(40%) space mtext("world")$ \
 $mtext("Hello") #box(width: 40%) mtext("world")$
 
+--- math-spacing-fractional-inline ---
+// Test fractional spacing in inline math.
+Hello #h(1fr) world \
+Hello $#h(1fr)$ world
+
+x #h(1fr) y \
+$x #h(1fr) y$
+
+Blah #h(1.5fr) long$#h(0.5fr) x - #h(1fr) y$ line. \
+Blah #h(1.5fr) long $#h(0.5fr) x - #h(1fr) y$ line.
+
+--- math-spacing-mixed-inline ---
+// Test mixture of different kinds of spacing in inline math.
+Some #h(30%) inline $x + #h(5%) y - #h(1fr) sum_(1 #h(1fr) 2) $ spacing #h(2fr) blah.
+Long $(a #h(1fr) z) #h(1em, weak: true)$ #h(1%) $#h(0.5fr) sqrt(1 + #h(0.5fr) y)$.
+
 --- issue-1052-math-number-spacing ---
 // Test spacing after numbers in math.
 $